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MKK3 K329 mutation attenuates diabetes-associated cognitive dysfunction by blocking the MKK3-RAGE interaction and inhibiting neuroinflammation

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Jinibixxi d-degradazzjoni tal-kollaen permezz ta' mekkanimi ta' mira doppja-: Inibixxi l-espressjoni tal-MMP: Jirregola l-espressjoni tal-eni MMP-1 (collagenase) u MMP-3 (matrilysin), u jnaqqas id-degradazzjoni enimatika tal-fibri tal-kollaen

10.3390/cells10092394 70 MatuszykM

Jason Brett, principal US medical head at Novo Nordisk, said, Were only the second FDA-approved treatment for MASH. He emphasized the need for better medications with stronger benefit-risk profiles that can also prevent disease progression